online sale U-47700's substitute U-48800
U-47700 has been replaced with U-48800. U-47700 HAS BEEN DISCONTINUED U48800 is member of the drug class opioid analgesics. Specifically U48800 belongs to the benzamide class of opioids. It is not used medically but within scientific research. U48800 has the systematic and formal IUPAC name 3,4-Dichloro-N-[(1R,2R)-2-(dimethylamino)cyclohexyl]-N-methylbenzamide. It has a molar mass of 329.27 grams and an empirical chemical formula of C 16 H 22 Cl 2 N 2 O. It was first developed by a team of researchers at the pharmaceutical firm Upjohn in the late 1970s. In animal models U48800 was shown to have potency 7.5 times greater than the classical medicinal opiate morphine. Pharmacologically U48800 is a selective agonist at the µ-opioid receptor with a Kd of 5.3 nM in contrast to a much weaker binding interaction at the kappa opioid receptor where U48800 have a Kd value of 910 nM. U48800 is a structural an...